From the airport or the port you.can take a taxi to bring you straight home its about 20 minutes ride and it will cost you 30-35 euros or you can take the bus to the City Center (Agora Stop) from there you need to walk to the house wich is not a long walk but with the suitcases won't be easy. Look up for the school yard and make left to Daskalogianni str all the way down then a right on Kalergon str. At 200 meters you see Funkies a pitsa place in the corner make a left there and the entrance of the house is the blue door on your right by the 2 Loux coffee shop