1. Firenze airport
Take A1 motorway, south direction ( Roma ) and exit "Firenze sud" gate.

1.1 Drive "Bagno a Ripoli", Pontassieve, "Passo della Consuma", Bibbiena, direction ( SR 70).

1.2. At Ponte a Poppi cross the Arno river to the village of Poppi and go to "Larniano" direction. One kilometer and half, after Larniano church, on the left there is the villa.

2. Pisa airport
Take the superstrada Firenze-Pisa-Livorno ( FI-PI-LI) close to the airport. Exit at Firenze and take motorway A1.
Then the same as paragraph 1.

3. Bologna airport.
Drive to Cesena by A1 motorway. At Cesena take superstrada E45 to "Bagno di Romagna".
Then go to "Passo dei Mandrioli", Badia Prataglia, Soci, Ponte a Poppi direction.
Then as 1.2 paragraph.

4.Roma airport.
Take motorway A1 to Arezzo, north direction. Exit Arezzo and follow indications as Subbiano, Bibbiena, Poppi.
At Ponte a Poppi as 1.2 paragraph.

At the airport you have to rent a car. The most important international companies have cars in any airport:
Hertz, Avis, Europcar, Maggiore... Rent the cheapest solution.